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In regards to water content, cream-vehicle treatment resulted in no changes in the mice subject to direct flame for 5 or 7 seconds

B12 injections are generally well-tolerated with mild injection site reactions, though rare hypersensitivity and hypokalaemia can occur, particularly when initiating treatment for severe deficiency

Certain groups are more likely to develop a deficiency, including: Vegetarians and Vegans (due to limited dietary sources) Adults over 50 (reduced stomach acid affects absorption) People with digestive conditions like Crohns disease or celiac disease Patients who have had weight-loss or gastrointestinal surgery Individuals taking medications like metformin or proton pump inhibitors (PPIs) Pregnant and breastfeeding women on plant-based diets When Should You Get Tested

Safety data in humans is limited, and therapy should only be considered under licensed medical supervision though research is still ongoing